MARCH 13, 2024 — Fertility requires proper development of egg and sperm. This development begins with an epic journey of egg and sperm precursors called primordial germ cells from their place of ...

The path of primordial germ cells illustrates the complexities of imprinted DNA, which contains epigenetic marks that turn on and off when necessary. Differences between the maternal and paternal ...

Two weeks after a human egg is fertilized, primordial germ cells (PGCs), which develop into sperm and eggs, are formed. In six to 10 weeks after fertilization, PGCs differentiate into pro ...

showed that rapidly extending and retracting blebs mediate motility in zebrafish primordial germ cells in vivo. Notably, cortical actin filaments were absent from the extending blebs, which ...