The prodrug strategy is basically a smart key that has been designed specifically to unlock the door to cancer treatment only when it reaches the correct target. Utilizing this prodrug strategy ...

Announcing a new publication for Acta Materia Medica journal. Prostate cancer (PrCa) is the most prevalent urogenital cancer affecting men. PrCa is marked by uncontrolled cellular growth that ...

and synthesized a bufalin prodrug to enhance the aqueous solubility (PLoS One 2015). However, due to its strong cardiotoxicity, bufalin has limited translational potential. A PROTAC is a ...