In living organisms, every protein—a type of biological polymer consisting of hundreds of amino acids—carries out specific ...

Finally, the single-stranded regions of DNA at the fork are covered by multiple copies of a single-strand DNA-binding protein ... to the above group of core proteins, other proteins (not shown ...

The CFTR Protein Distribution Core offers high-quality ... Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1. Biochim Biophys Acta, ...

To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid ... the basic structural units of chromatin composed of a histone core wrapped with DNA. At the ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

Other DNA binding proteins tend to be less picky in sequence ... forms the binding site for the σ 70 subunit of the core RNA polymerase. However, despite the high degree of conservation at ...

So how does protein synthesis make hair? If you've looked at the activity (or even the text version of the activity), you know how a section of DNA instructs a cell how to make a protein.

the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a 20-DNA-letter long sequence that matches part of the guide RNA sequence.

“At any rate, it will be exciting to see whether this DNA binding mode is a general phenomenon for bacterial histones.” Clarification (February 2): Dame’s comments have been amended to clarify that ...

In some, the RNA-binding region is adjacent to a DNA-cutting part of the protein. Others appear to bind to other proteins, ...

The NMR and Drug Metabolism Core works ... to a unique DNA sequence that acts as a “bar code” defining its synthesis, can be incubated in a single tube with a target protein and subjected to washes to ...