RNA modifications play crucial roles in gene regulation, cellular function and the response to environmental stimuli. However, the detection and characterization of these modifications remain ...
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the ...
A northern blot is a laboratory method used to detect specific RNA molecules among a mixture of RNA. Northern blotting can be used to analyze a sample of RNA from a particular tissue or cell type ...
The Rice team's new method, called RNA-addressable modification (RAM), bypasses these hurdles by using a synthetic catalytic RNA (cat-RNA) to "barcode" ribosomal RNA (rRNA) inside living cells.
However, RNA is typically single-stranded and serves various functions, such as coding for proteins (mRNA), transferring amino acids (tRNA), and catalyzing biochemical reactions (ribozymes). Cytosine ...
Gaining an understanding of RNA epigenetic modifications offers opportunities for identifying new biomarkers and drug targets that are associated with diseases such as cancer and neurological ...
A northern blot is a laboratory method used to detect specific RNA molecules among a mixture of RNA. Northern blotting can be used to analyze a sample of RNA from a particular tissue or cell type ...
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