This polymerase contains four catalytic subunits ... For example, researchers know that RNA pol II can bind to a DNA sequence within the promoter of many genes, known as the TATA box, to initiate ...

Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do. Moreover, each step in the flow of ...

“It didn’t look like it was RNA polymerase. Therefore, it was probably histones ... To test the accuracy of the method, Ren and his colleagues monitored the DNA binding sites of two transcriptional ...

New research pioneered by The University of Western Australia is shedding light on the intricate dance between proteins, DNA ...

This process is carried out by the enzyme RNA polymerase, which binds to specific promoter regions on the DNA and initiates the synthesis of ... These small RNAs can bind to complementary mRNA ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

The team focused on T7 DNA polymerase’s thioredoxin binding domain (TBD), which has a structure similar ... A Simple Solution for High-Throughput Full-Length Single Cell RNA Sequencing Singleron ...

In the pursuit of understanding the pathogenic expression mechanisms of bacteria and the advancements in biofoundry ...

Polymerase Chain Reaction is a widely used technique in molecular biology for amplifying specific DNA sequences. The process relies on the use of pyrimidine-containing primers that bind to the target ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results from a combination of higher Pol II turnover and lower transcription ...

In the process, DNA ... RNA motifs must be selected and translated into a genetic template that is ultimately synthesized as an artificial gene. To implement the blueprint it contains, RNA ...