Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

RNA polymerase is an enzyme that is responsible ... there are striking similarities among transcriptional mechanisms. For example, all species require a mechanism by which transcription can ...

The findings demonstrate that, under certain circumstances, the RNA polymerase (RNAP ... so cells have many redundant mechanisms to prevent them from forming," says Seth Darst, head of the ...

A global team has made a significant advance in understanding how bacterial plasmids contribute to antibiotic resistance.

The goal of my research is to understand the mechanisms and structures of enzymes that perform and regulate essential nucleic acid transactions. My research integrates diverse experimental approaches ...