Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

Once transcription is initiated, the DNA double helix unwinds and RNA polymerase reads the template strand, adding nucleotides to the 3′ end of the growing chain (Figure 2b). At a temperature of ...

Shawna was an editor at The Scientist from 2017 through 2022. She holds a bachelor's degree in biochemistry from Colorado College and a graduate certificate and science communication from the ...

An enzyme called RNA polymerase deciphers this code and converts it into RNA, a molecule that closely resembles DNA. This transfer of life's code from DNA to RNA is called transcription.

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small cell lung cancer (NSCLC) and small cell lung ...

RNA synthesis, or transcription, is the process by which RNA is produced using DNA as a template. This process is carried out by the enzyme RNA polymerase, which binds to specific promoter regions on ...

For natural cells, the so-called central dogma of molecular biology describes how protein synthesis occurs through transcription ... the blueprint it contains, RNA polymerase is used.

A new study identifies a blood-based biomarker that detects pre-symptomatic Parkinson’s disease by measuring the ratio of ...

For natural cells, the so-called central dogma of molecular biology describes how protein synthesis occurs through ...

Ibrahim Cissé spent hours as a child taking apart and trying to rebuild electronics. Other times, he would reenact NASA space shuttle liftoffs, tipping a chair backward onto the floor and then ...

Our mission is to elucidate fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in ...