Transform your drug development pipeline with Newcells’ Renal Proximal Tubule Cells Model eBook. This eBook provides insight into the science behind aProximate ™, an innovative proximal tubule ...

Three different hTERT-immortalized human primary renal proximal tubule epithelial cells (RPTEC) were modified and tested for functionality and stable expression of the OAT1, OCT2, and OAT3 proteins.

[21] Many other cells can be seen in urine and are of variable clinical significance. Renal tubule epithelial cells can be oval to columnar in shape, depending on the segment of the tubule they ...

Among the findings, Susztak and her colleagues discovered that proximal tubule cells are one "hotbed" of disease-causing variants. These cells play various kidney-function roles including ...

Renal cell carcinoma (RCC) refers to a heterogenous group of cancers that originate in the proximal convoluted tubule of the kidney. The three most common forms of RCC are clear cell RCC ...

The work included in vitro renal transporter studies using Newcells' aProximate TM model, comparing proximal tubule cell flux in rats, dogs, and humans. The data was analyzed to provide a ...

A treatment for polycystic kidney disease(PKD), a leading cause of fatal kidney failure worldwide, has been identified by a research team led by Yale biochemist Craig Crews A treatment for ...

Each kidney contains over one million microscopic filtering units called nephrons. Each nephron is made of a tubule and is responsible for 'cleaning' the blood by removing urea and excess water ...

interstitial cells have been shown to express erythropoietin messenger RNA, even in advanced chronic kidney disease; cysts derived from proximal tubules, but not those derived from distal tubules ...