A new study from Yeshiva University has revealed a surprising finding—some widely used medications for high blood pressure ...

The last introduction of a new class of antihypertensive drugs, called renin inhibitors, was in 2007 with the approval of Tekturna (aliskiren). Not only are endothelin receptors a new class of ...

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...

BACKGROUND: Limited evidence exists on the prognostic role of continuing medical therapy in patients with heart failure (HF) and an ejection fraction (EF) that has improved over time. This study ...

These agents include angiotensin-converting-enzyme (ACE) inhibitors, angiotensin-receptor blockers (ARBs), mineralocorticoid-receptor antagonists, and direct renin inhibitors, all of which can ...

The study focused on why people with severe high blood pressure often develop thickened arteries and small blood vessels in ...

New small-molecule inhibitors are being developed as well; Basel-based Novartis received approval for Tekturna (aliskiren), a direct renin inhibitor, just last year. Aldosterone synthesis ...

A reasonable strategy would be to stop the ACE inhibitor and start a diuretic. If the renin level is high, then it might be reasonable to add either a ß blocker or an angiotensin receptor antagonist.