Export of protein molecules across the bacterial membranes takes place via a variety of mechanisms, from simple one-component systems to complex multicomponent pathways, with five types of ...

You can think of the bacteria as little factories that are pumping ... Our expertise in understanding secretion machinery was essential in order to build this system. Aparna is a freelance science ...

How does bacterial conjugation work and what’s the role of the ... The second set encodes proteins for mating-pair formation (MPF), a type IV secretion system (T4SS) that delivers DNA from the donor ...

Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular ...

Researchers from the Mekalanos laboratory were interested in investigating the T6S system (T6SS ... of post-translational control of bacterial secretion.

Certain bacteria outcompete rivals and fend off attackers by injecting them with a lethal cocktail using tiny, nano-sized spearguns, known as type VI secretion systems (T6SS). Pseudomonas bacteria ...

We hope to use this new method to elucidate the evolutionary constraints on proteins that use the type III secretion system of gram negative bacteria. My newest project aims to measure the unfolding ...