Hypertonic saline refers to any saline solution with a concentration of sodium chloride (NaCl) higher than physiologic (0.9%). Commonly used preparations include 2%, 3%, 5%, 7%, and 23% NaCl.

and hypertonic saline cannot be recommended over 0.9% sodium chloride injection or lactated Ringer's solution at this time. Of note, patients with burns were excluded from the two studies funded ...