Researchers reveal the molecular mechanisms of Streptomyces platensis’s defense from its own antibiotics, which inhibit fatty acid synthesis in other microbes. Jef Akst was managing editor of The ...
A natural antibacterial molecule shows clinical promise. Its unusual binding site is on an excellent target: ...
Mandimycin, which targets a different essential fungi cell resource than other antifungal drugs, should harm other cell types as collateral — but doesn’t.
The National Institutes of Health awarded its highly competitive Research Grant Project to Cole Stevens, an associate ...
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Bacterial 'jumping genes' can target and control chromosome endsIn Streptomyces—historically one of the most significant bacteria for antibiotic development—they found that transposons controlled the telomeres in nearly a third of the chromosomes.
In Streptomyces – historically one of the most significant bacteria for antibiotic development – they found that transposons controlled the telomeres in nearly a third of the chromosomes.
The insights—especially into Streptomyces, which is difficult to manipulate in the lab and accounts for the discovery of many of our antibiotics—could prove useful for drug development ...
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