Hitting the target: Imaging reveals psilocybin's neural odyssey
Psilocybin is the active ingredient that gives so-called "magic mushrooms" their hallucinogenic kick. It also has a ...
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A high-resolution 'map' reveals the structural and functional complexity of endogenous NMDA receptors in the brain
In this study, researchers first enriched eNMDARs from brain tissue of adult wild-type rats using a high ... and GluN1-N2B di-heteromeric receptors. These structural discrepancies of the subunit ...
Nature4y
Structure and signaling of Toll-like receptors
A) The structure of TLRs is characteristic of type I membrane proteins ... The ligand binds to a site in the extracellular domain of the receptor (not shown) and induces a conformational change ...
Critical blood defense receptor CD163 mapped for first time
CD163 might not be the most exciting name in the world, but behind it lies one of the body's most important defense receptors ...
Nature12y
Toll-Like Receptors: Sensors that Detect Infection
Recall that different cell types of a multicellular organism ... Liu, L. et al. Structural basis of Toll-like receptor 3 signaling with double stranded RNA. Science 320, 379–381 (2008) doi ...