Cells sustain their purine levels through two pathways: De novo synthesis builds purines from scratch, whereas the salvaging route uses intermediate metabolites, such as those obtained from the diet.

The FDA reviewed this test under the FDA’s De Novo premarket review pathway, a regulatory pathway for low- to moderate-risk ...

Lignans are low molecular weight polyphenolic compounds with important antitumor and antiviral properties. However, their low amounts in medicinal plants and complex structures make sustainable ...

but can also drive de novo centriole assembly in unfertilized eggs that initially lack centrioles. These studies offer a new perspective on the mechanisms that control centriole duplication.