but little is known about the fidelity of transcriptional initiation by RNA polymerase II in vivo. I suggest that ∼90% of Pol II initiation events in yeast represent transcriptional noise ...

There are a variety of different types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is responsible for creating messenger RNA (mRNA), which is the main ...

In the model system I study, Saccharomyces cerevisiae (Baker’s yeast), the RNA polymerase enzyme is aided by many proteins known as elongation factors. These factors may be involved in dealing with ...

Thus, transcriptional control is dependent on the interactions of all the TFs and whether they attract RNA polymerase or block ... as described earlier, yeast have no enhancers but instead use ...

Overview of RNA repair – There is an emerging appreciation of the existence ... where a single multifunctional tRNA ligase enzyme (Trl1 in yeast; AtRNL in Arabidopsis) repairs the ends of the broken ...