The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

Thus, the elongation period of transcription creates a new mRNA molecule from a single template strand of DNA. As the mRNA elongates, it peels away from the template as it grows (Figure 5).

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

The journey of mRNA begins in the cell nucleus, where it is synthesized through a process called transcription: Through this process, mRNA serves as the critical link between the genetic information ...

Transcription initiation sites are locations in the DNA where a specialized transcription-factor protein can attach and then build an mRNA copy of the gene in front of it.

2 Located throughout the pre-mRNA are short, cis-acting motifs consisting of five to six nucleotides that are binding sites for RBP, which act in trans. 1,8 “When an exon that is alternatively spliced ...

Oracle Chairman Larry Ellison highlighted the potential medical benefits of the investment, stating that AI could be used to detect cancers and customize mRNA vaccines to treat them within 48 hours.

templates for in vitro transcription (IVT) synthesis of mRNA molecules. Alchemy cell-free DNA technology is now available at research grade, providing researchers with a faster, more efficient ...

There have been 67 confirmed human bird flu cases in the U.S. since April 2024. Moderna has been awarded approximately $590 million from the federal government to help speed up the development of ...

We found that inclusion or exclusion of the 3′UTR of an mRNA that encodes a transcription factor did not change how much of the transcription factor protein was expressed but determined the location ...