Quarterback Brock Purdy will not be available to play in the 49ers’ season finale against the Arizona Cardinals on Sunday.

Never before in NFL history have two teams with at least 14 wins each gotten together for a regular-season matchup. But that ...

NFL Draft is on the horizon, and it is expected Cam Ward or Shedeur Sanders will be the first player off the board.

The stage is set for the biggest regular season game in NFL history as the Detroit Lions take on the Minnesota Vikings on ...

The San Francisco 49ers came out swinging against the Detroit Lions in Week 17, taking a 21-13 lead into halftime. However, the Lions pounced in the second half, putting up 27 points to complete a ...

In this Week 18 game preview, J.B. Long looks back at the importance of the Week 9 OT win at Seattle, looks ahead to quarterback Jimmy Garoppolo’s season debut, and details just how much the rookie Pr ...

Nick Khan’s prediction becomes a reality on Monday night. The World Wrestling Entertainment executive said during earning ...

Jennifer Lee Chan shares the latest injury report for Sunday's San Francisco 49ers vs. Arizona Cardinals game.

San Francisco 49ers quarterback Brock Purdy exited Monday night's shootout with the Detroit Lions in the final two minutes, as the Niners were driving for a late touchdown to cut the Lions' lead to ...

The Seahawks hit the road for the final time this season as they get set to take on the division rival L.A. Rams in Week 18. Seahawks reporter Jen Mueller breaks down the Seahawks' final game of the ...

This year, Detroit surged to a 12-1 record to start the season and has been one of the top teams in the NFL for months. Both Lions' losses -- a 20-16 setback against Tampa Bay and a 48-42 defeat at ...

Former Pittsburgh Steelers quarterback Josh Dobbs will start for the San Francisco 49ers in their game against the Arizona ...