Clinically significant hyperkalemia reduces membrane excitability and disturbs the acid-base balance, manifesting as weakness, flaccid paralysis, hypoventilation, and metabolic acidosis.

electrolyte and acid–base abnormalities (symptomatic hyponatraemia, metabolic acidosis and severe dehydration), metabolic abnormalities (hypoglycaemic coma and diabetic coma), respiratory (severe ...

Am J Health Syst Pharm. 2008;65(15):1430-1434. Kathryn D. Mathews, PharmD, is Cardiology Clinical Pharmacist, Intermountain Medical Center, Murray, UT; at the time of writing, she was Cardiology ...

It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection force for cancer cell somatic evolution. Acidic pH has pleiotropic effects on the proliferation, ...

Here, we experimentally examined diet-microbe- host interactions through a complex systems framework, centered on dietary oxalate. Using multiple, independent molecular, animal, and in vitro ...

Metabolic syndrome is a disorder of energy use and storage. This syndrome is characterized by central obesity, dyslipidaemia, raised blood pressure and high blood sugar levels. Patients with ...

Kidney disease encompasses a complex set of diseases that can aggravate or start systemic pathophysiological processes through their complex metabolic mechanisms and ... and environmental acid-base ...