Hosted on MSN14d
Major step in return of the mammoth after scientists create ‘woolly mouse’
Changes to melanin production created a golden mouse rather than the black/agouti wild type coat color. Colossal woolly mice have changes in body weight due to changes in lipid metabolism and fatty ...
The Scientist10mon
Classic Mechanism of Epigenetic Inheritance Is Rare, Not the Rule
The mice are Agouti Viable Yellow, naturally occurring mutants, which, though genetically identical, have coats that vary in color—a phenomenon that researchers have long studied as an example of ...
Nature1y
Obesity, Epigenetics, and Gene Regulation
For instance, in normal, healthy mice, the agouti genes are kept in the "off" position by the epigenome, which attaches methyl groups to the corresponding regions of DNA, resulting in the DNA's ...
Business Wire14d
Colossal Creates the Colossal Woolly Mouse, Showcasing Breakthroughs in Multiplex Genome Editing and Trait Engineering on the Path to a Mammoth
that produces mice with golden hair rather than the black/agouti wild type coat color. Colossal woolly mice also express a truncated version of fatty acid binding protein 2, or FABP2, reflecting a ...
Nature1y
Cloning of male mice from adult tail-tip cells
The remaining male pup developed into a fertile adult male with the same agouti coat colour as the B6C3F1 tail-tip cell donor. As oocytes of B6D2F1 mice do not carry the agouti mutation ...
GEN - Genetic Engineering and Biotechnology News13d
Colossal’s Multiplex-Edited Mice Replicate Woolly Mammoth Hair Traits
By combining three editing technologies, Colossal engineered mice that express multiple mammoth-identified traits relevant to cold adaptation.
Metro14d
Major step in return of the mammoth after scientists create ‘woolly mouse’
Changes to melanin production created a golden mouse rather than the black/agouti wild type coat color. Colossal woolly mice have changes in body weight due to changes in lipid metabolism and ...