lung.mas.lu.se Background: Neonatal screening for alpha 1 –antitrypsin (AAT) deficiency was undertaken in Sweden between ... and a questionnaire on smoking habits and respiratory symptoms. Conclusions ...

uv.es Background Recent investigations in animal models have revealed oxidative stress and oxidative damage in the pathogenesis of alpha-1 antitrypsin deficiency (AATD ... AATD-related emphysema ...

Liver diseases can be inherited (such as Wilson disease and alpha 1-antitrypsin deficiency) or acquired (for example hepatitis and liver cancer). The performance of AAV gene-therapy vectors is ...

Serum specimens from 93 members of six families and three additional persons in the United States with serum alpha1-antitrypsin deficiency ... the Quantity of Alpha 1-Antitrypsin (Abscissa ...

Shares in Wave Life Sciences rose by 74% after it reported clinical data with a pioneering new RNA-editing therapy for alpha-1 antitrypsin ... lung symptoms, but have no impact on the liver ...

Despite promising Phase 3 results, safety concerns, namely liver injury, have impacted Agios stock and could affect Pyrukund's approval and market adoption. Read the full report here.

The liver had diffuse hypoattenuation with a ... measurement of ceruloplasmin and alpha 1-antitrypsin, and screening for human immunodeficiency virus infection. Antinuclear antibodies, anti ...

"Asthmatic bronchitis" describes people with asthma and bronchitis symptoms ... also result from alpha-1 antitrypsin deficiency. This genetic condition can cause lung and liver disease.

and alpha-1-antitrypsin deficiency) liver diseases, hepatic malignancies, hepatobiliary infections, and biliary tract disease should be excluded before ascribing abnormal liver tests to NAFLD.

It’s produced by your liver and then released into your bloodstream. People with low levels of AAT have a condition called alpha-1 antitrypsin deficiency ... If your symptoms are being caused ...

In August 2024, Agios also reported topline results from the ACTIVATE-KidsT Phase 3 study of mitapivat in children aged 1 to <18 ... “PK deficiency can lead to debilitating fatigue and a range of ...