The researchers confirmed that the increased production of hydrogen peroxide did not impede the function of mitochondria. They investigated a form of apoptosis caused by hydroxy radicals formed in the ...

Rotenone, an inhibitor of the mitochondrial electron transport chain, prevented ROS generation and apoptosis in response to edelfosine in S cerevisiae. α-Tocopherol abrogated the edelfosine ...

In Ming-Chiu Fung’s immunology lab, Hogan had been investigating how disturbances in the cytoskeletons of cells might contribute to the fragmentation of mitochondria during apoptosis, the most ...

Mitochondria determine whether a cell lives or dies via the process of programmed cell death, or apoptosis. Attempts to build ...

In particular, mitochondrial Ca 2+ plays a dual role: enabling physiological functions like metabolism and ATP synthesis while contributing to pathological processes such as apoptosis and ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death. Mitochondrial Ca2+ ...