thorax.bmj19d
Randomised trial of CPAP vs bilevel support in the treatment of obesity hypoventilation syndrome without severe nocturnal desaturation
Conclusions: Both CPAP and BVS appear to be equally effective in improving daytime hypercapnia in a subgroup of patients with obesity hypoventilation syndrome without severe nocturnal hypoxaemia.
Frontiers3y
Mechanisms of Hypercapnia-Induced Endoplasmic Reticulum Dysfunction
Recent evidence suggests that both acute and chronic hypercapnia (elevated levels of CO 2) impair ER function by different mechanisms, leading to adaptive and maladaptive regulation of protein folding ...
Frontiers3y
TRAF2 Is a Novel Ubiquitin E3 Ligase for the Na,K-ATPase β-Subunit That Drives Alveolar Epithelial Dysfunction in Hypercapnia
Several acute and chronic lung diseases are associated with alveolar hypoventilation leading to accumulation of CO 2 (hypercapnia). The β-subunit of the Na,K-ATPase plays a pivotal role in maintaining ...