whereas the inhibition of autophagy can sensitize cancer cells to chemotherapy to promote p53-induced apoptosis. Thus, manipulation of autophagy can determine cell-fate decisions in clinical settings.

Rett syndrome is a rare genetic disease affecting 1 in 10,000 newborn girls, characterized by sudden regression around 1 year ...

Guan's lab has focused on how autophagy, or the cell's "recycling" function, affects cancer metastasis. "Autophagy can be ...

Liver Health: Autophagy may prevent damage caused to the liver by alcohol, drugs, or conditions known as fatty liver. Cancer: While autophagy may inhibit early tumor growth by removing damaged ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...

Impaired autophagy is linked to cardiovascular diseases, neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease, metabolic disorders like diabetes and cancer. Various ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals.

How mitochondria drive autophagy Date: February 13, 2025 Source: Institute for Research in Biomedicine (IRB Barcelona) Summary: A new study unravels the relationship between mitofusins ...