Autophagy is the process by which cells digest and renew their internal structures, recycling damaged or malfunctioning ...

Headed by Drs. Antonio Zorzano and Saska Ivanova, a study published in the journal Autophagy unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing ...

Autophagy can mediate the specific removal of stressed or damaged cytoplasmic organelles, including mitochondria and the ER. Undoubtedly, there are multiple connections between the apoptotic and ...

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial ...

Researchers from the University of Bergen, for the first time, show how mitochondria act as “reservoirs” to hold NAD, which plays an important role in creating energy in the body. Scientists ...

In assessing biological age, factors such as epigenetic changes, telomere length, oxidative damage, and mitochondrial dysfunction in rescue mechanisms such as autophagy all play major roles. Recent ...

Mitochondrial autophagy (or mitophagy) regulates the mitochondrial network and function to contribute to multiple cellular processes. The protective effect of homeostatic mitophagy in cardiovascular ...

This work represents a novel and significant contribution to the field, revealing for the first time that the loss of mitochondria from axons can lead to impaired autophagy function via eIF2β, ...

Mitochondria are more than the powerhouses of the cell, they regulate a plethora of cellular processes such as apoptosis, metabolism and signaling. This exciting collection highlights the most recent ...

One of their survival strategies is autophagy, a process in which cells degrade and recycle waste products. This mechanism not only allows cancer cells to expel anticancer drugs but also provides ...