Advances in vaccine technology and the road ahead
Explore the evolution of vaccine technology from Jenner to mRNA, highlighting India's role in COVID-19 vaccine development.
Targeted Oncology13h
CAR T-Cells Demonstrate Efficacy, Tolerability in Early-Relapsed DLBCL
During a Case-Based Roundtable® event, Natalie Galanina, MD, discussed data from the ZUMA-7 and TRANSFORM trials in the first ...
Science Daily16h
Digging into a decades-old hepatitis B mystery suggests a new potential treatment
In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, researchers have identified a vulnerability that opens ...
Nona Biosciences Announces Licensing Agreement With The University Of Alabama At Birmingham To Support B Cell Development Research
CAMBRIDGE, Mass., Feb. 19, 2025 /PRNewswire/ -- Nona Biosciences, a global biotechnology company providing a total solution from "Idea to IND" (I to I TM ), today announced a licensing agreement with ...
Dysfunctional B cells: A novel target for cancer immunotherapy and diagnostics
University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of ...
Healio3d
FDA accepts IND for allogenic CAR T-cell therapy that could bypass lymphodepletion
The FDA has accepted an investigational new drug application for ALLO-329, an allogeneic chimeric antigen receptor T-cell ...
gut.bmj4d
Reparative immunological consequences of stem cell transplantation as a cellular therapy for refractory Crohn’s disease
Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...
Targeted Oncology6d
Jain and Participants Consider BTK Inhibitor Resistance in CLL
During a Case-Based Roundtable® event, Nitin Jain, MD, and participants discussed treating a patient with CLL after ...
Le Lézard6d
Early Glycan Screening: Key to High-Quality Biologics Development, Upcoming Webinar Hosted by Xtalks
TORONTO, Feb. 14, 2025 /PRNewswire-PRWeb/ -- Early glycan screening is a cornerstone for ensuring long-term biologic quality and accelerating decision-making in cell line development (CLD). Glycan ...
The EMBO Journal8d
Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation
In 2020-2021, a mysterious skin disease affected fishermen in Senegal. High levels of Portimine A toxin, produced by the ...
eLife10d
Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of Osteoarthritis
This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...
gut.bmj18d
Impact of HBsAg and HBcrAg levels on phenotype and function of HBV-specific T cells in patients with chronic hepatitis B virus infection
Hepatitis B virus (HBV)-specific T cells are exhausted and impaired in patients with chronic ... For analysis of T cell restoration, anti-programmed cell death ligand 1 (anti-PD-L1, clone M1H1, ...