State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China Department of Medicinal Chemistry, School ...

ELYSA, endosomal-lysosomal organellar assembly. GV oocytes were incubated for in vitro maturation (IVM) for 18 h with or without actin polymerization inhibitors (10 μM latrunculin A or cytochalasin B) ...

Common lysosomal inhibitors include Bafilomycin A1 (BafA1), chloroquine (CQ), and hydroxychloroquine (HCQ). A systematic review and meta-analysis of all cancer trials that have been undertaken using ...

Alpha-synuclein (α-syn), a major component of Lewy bodies found in Parkinson’s disease (PD) patients, has been found exported outside of cells and may mediate its toxicity via cell-to-cell ...

To monitor autophagic flux, cells were exposed to TNF-α or vehicle with or without the lysosome inhibitor BafA1 at 24 h post-transfection with tf-LC3 plasmids. The yellow and red LC3 puncta were ...