Switching from beta-blockers to digoxin as first line therapy for older patients with AF could produce £100m in NHS savings annually.

The following is a summary of “Cost-effectiveness of digoxin versus beta blockers in permanent atrial fibrillation: the Rate Control Therapy Evaluation in Permanent Atrial Fibrillation (RATE-AF) ...

One crucial unanswered question is the dosing of β blockers. In the COPERNICUS trial, [24] the target dose of carvedilol was 25 mg b.i.d, and in the US Carvedilol trials, [28] patients weighing ...

The dose of the first- or second-generation β blocker that the patient is receiving is an important consideration for the switching regimen chosen. The major factors to be kept in mind when ...

Health Minister Mark Butler said that interim advice on the use of one part of that treatment, puberty blockers, will be completed in the middle of next year. That treatment was banned last year ...

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