Dr. Jin noted that ETX-636 is the second novel ENSEM compound entering clinical development. ETX-197, an oral selective CDK2 inhibitor licensed to BeOne and being developed as BG-68501, is currently ...

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

Researchers have uncovered the 3D structure of RBP3, a key protein in vision, revealing how it transports retinoids and fatty ...

Proteins are fundamental biomolecules that perform a broad range of vital functions within the human body. They serve as an essential structural and functional component of cells, tissues and organs ...

Array Bridge is testing promising drug candidates that can effectively bind and even degrade target proteins, but not via ...

A trisaccharide unit on the human cell receptor for H5N1 avian influenza, SA-α(2-6)-Gal-β(1-4)-GlcNHAc, was also prepared; this was the first one-pot synthesis of this trisaccharide unit.

Abstract Guanylate cyclase-A, the receptor for atrial natriuretic factor, contains a protein kinase–like domain and a catalytic domain in the intracellular region. To investigate the active site (the ...

Washington State House Bill 2153, developed with the help of the King County Prosecuting Attorney’s Office, is now in effect, adding laws to deter catalytic converter theft in Washington state ...

Get Instant Summarized Text (Gist) A novel drug compound has been identified that selectively activates delta opioid receptors, offering pain relief without the dangerous side effects associated ...