Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

During this stage, one set of chromosomes is pulled to the sides of the cell and the nucleus divides. The phases of mitosis are known as prophase, metaphase, anaphase and telophase. You do not ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Indeed, before entry into anaphase, the RanGTP gradient ... essential functions in different parts of the cell cycle. In interphase, it orchestrates the nucleo-cytoplasmic transport, while in mitosis ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

Researchers observed an increase in both CXCR4 and CD5 levels as the cells progressed to later stages of the cell cycle, particularly in the S/G2/M phases.