3D structure of the social amoeba genome sheds light on the transition to multicellularity
Each cell of the human body contains two meters of DNA. The whole secret lies in the intricate three-dimensional arrangement ...
How do cells respond to changes? New study finds it's not all in the genes
Cells are constantly on the move, whether in a developing embryo or metastatic cancer. But how do cells adapt to the new ...
Science Daily1d
Breakthrough study challenges long-held beliefs about the shape of atomic nuclei
An international research collaboration has overturned the long-standing belief that the atomic nucleus of lead-208 is perfectly spherical. The discovery challenges fundamental assumptions about ...
Unraveling structure and function relationships in synthetic cell receptors
Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...
eLife1d
PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation
This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...
HIV protein switch may help virus squeeze into host cell nucleus
Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ...
Chemistry World4d
AI inspired by AlphaFold can predict chromatin structures found in chromosomes
Zhang and his colleagues designed a generative AI model called ChromoGen to quickly ‘read’ DNA sequences and predict the ...