First, the three disorders have distinct anatomical patterns of degeneration: PSP is associated with extensive pathological changes in the cerebellum and pons, whereas CBD, PNFA and FTD generally ...

Background Guidelines regarding recommendations for surgical treatment of spontaneous cerebellar intracerebral haemorrhage (ICH) differ. We aimed to systematically review the literature to assess ...

This can lead to pain and other symptoms. Most people will have some disk degeneration by 40 years of age, but they may not always experience pain. This condition can also be caused by injury and ...

eLife Assessment Using a unique cerebellar disruption approach in non-human primates, this study provides valuable new insight into how cerebellar inputs to the motor cortex contribute to reaching.

Macular degeneration is very common and affects an estimated 19.8 million people in the United States. Approximately one in 10 Americans age 50 and older have an early form of the disease and as many ...

Retinitis pigmentosa is a relatively rare genetic disorder (affecting 1 in 3,500 people), while age-related macular degeneration affects 7–8% of the population, and its incidence increases with age.

In the summer of 1977, Yosef Shiloh, then a graduate student, visited an Israeli Moroccan Jewish family with several children affected by ataxia-telangiectasia (A-T), a rare and complex genetic ...

Macular degeneration causes vision loss and primarily affects people age 65 and older. The condition affects the macula, the sensitive part of the retina responsible for sharp, central vision. There ...

a comprehensive description of the events leading to the development of motor impairment and degeneration is still lacking. However, in the last years the possible causal role for altered cerebellar ...

Introduction: Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant, cerebellar degeneration predominant disease caused by excessive CAG repeats. We examined ...