Cubs vs Padres Prediction, Odds, Picks - Apr. 4

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Chicago Cubs vs. San Diego Padres live stream, TV channel, start time, odds | April 4
Get Chicago vs San Diego baseball betting preview, spread and over/under insights for their matchup on April 4.
Chicago Cubs vs. San Diego Padres odds, tips and betting trends | April 4
Two clubs on winning streaks — the San Diego Padres (seven straight) and the Chicago Cubs (three in a row) — play on Friday at 2:20 p.m. ET, at Wrigley Field.The Cubs are a home
Padres at Cubs Prediction: Odds, expert picks, starting pitchers, betting trends and stats for April 4
The Cubs are back at Wrigley following a three-game smackdown of the Athletics in Sacramento. Chicago outscored the Athletics 35-9 in the series. Wednesday, Seiya Suzuki homered twice and drove in five runs to power the Cubs to a 10-2 win.

Chicago Cubs, Wrigley Field

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When is the Cubs home opener? What to know ahead of season's 1st game at Wrigley Field
The Chicago Cubs may be nine games into their 2025 MLB season, but they've yet to play in front of their home fans at Wrigley Field. That changes Friday afternoon, when the Cubs will host the undefeated San Diego Padres.
Wrigleyville community preparing for Chicago Cubs home opener: 'Great atmosphere'
The Chicago Cubs finally have their home opener Friday after starting on the road. The baseball season brings a boost to Wrigleyville businesses.
A brief history of Chicago Cubs home openers
But the first Cubs home opener was not held at Wrigley Field — it happened many years before the ballpark was built — and the first professional baseball home opener at Wrigley Field was not a Cubs game.
Chicago baseball report: Colin Rea steps up for Cubs — and White Sox starters put together impressive streak
The Cubs are finally home. And the White Sox hit the road for the first time this season with series against the Detroit ...
Cubs Are Getting Exactly What They Paid For When They Acquired Their Superstar
The Chicago Cubs are fully back on track after what was a tough beginning to the season when they suffered back-to-back losses in Japan to the defending World S ...
Cubs' Tucker Proved He Earned His Spot in the NL Central Hitter Power Rankings
While it could have been considered impossible by some, Kyle Tucker is somehow exceeding Cubs fans' sky-high expectations ...
Bleed Cubbie Blue on MSN14h
Here are all the former Cubs around MLB in 2025
Here are the 42 former Cubs (and 21 coaches/managers) currently on 40-man rosters (or injured lists) for those other 29 teams ...
Newest Cubs Superstar Predicted To Join Elite Company on All-MLB Team
With the highly anticipated year starting up for the Chicago Cubs, the franchise will be looking to build some momentum in ...
Chicago Cubs help Athletics open their new-to-them ballpark in West Sacramento: ‘It’s a new baseball experience’
The Chicago Cubs are part of the first major-league series played at Sutter Heath Park, a Triple-A stadium the Athletics are ...
Kelly hits for cycle and Cubs power past Athletics 18-3 in 1st MLB game at Sutter Health Park
Carson Kelly hit for the cycle and drove in five runs, Michael Busch launched a two-run homer on the way to a career-high ...
Chicago Cubs Pete Crow-Armstrong Predicted to Lead MLB in Stolen Bases
Bleacher Report's Joel Reuter made one bold prediction for every MLB team this past Saturday. Reuter's Chicago Cubs ...