How do antibody engineers select isotypes ... Human IgG4 was exchanged for human IgG1 within the constant region of keliximab, and two variants (IgG4-E and IgG4-PE) were tested.

Epsilogen completes acquisition of TigaTx to create world’s leading pan-isotype cancer antibody company: London Tuesday, April 8, 2025, 10:00 Hrs [IST] Epsilogen, the global lea ...

Epsilogen, the global leader in the development of immunoglobulin E (IgE) antibody therapeutics, today announces that it has completed the acquisition of TigaTx, Inc., a biotechnology company ...