The normal “wild types” of the huntingtin protein play a synaptic function required ... An increasing number of studies have shown that mutant Htt proteins can affect negatively biomolecules, ...

Leo's leadership is tested by the Kraang, challenging his calm demeanor. Nickelodeon revamps TMNT in 2012, successfully combining comedy and adventure. Leo's emotional struggles and family loyalty ...

The neuronal accumulation of mutant huntingtin is a hallmark of Huntington's disease. New research shows that post-translational modifications of the mutant protein promote its clearance ...

They include the dysregulation of the expression of thousands of genes in the striatal neurons and an accumulation of clumps of mutant Huntingtin protein (called aggregates), which are a hallmark ...

With Call of Duty: Black Ops 6 now awash with creepy dolls and luridly magenta jumpsuits courtesy of its recent Squid Game collaboration, Activision's FPS is ready for another pop culture invasion ...

It’s not much of a hyperbole to say that Chris Claremont created the modern X-Men as we think of them today. So we get excited any time Claremont returns to Marvel’s Merry Mutants, especially ...

1st issue sold out at distributor level, 2nd printing out on March 12 Jorge Corona drew the second printing's new cover. Image courtesy of IDW Publishing A black and white variant of the new cover ...

Huntington’s is a progressive neurodegenerative disease caused by an inherited mutated copy of the huntingtin gene. Symptoms like uncontrolled movements and trouble with mobility and cognition ...

They include the dysregulation of the expression of thousands of genes in the striatal neurons and an accumulation of clumps ...

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...