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The superfamily 1 (SF1) and SF2 enzymes are non-hexameric enzymes possessing both helicase and single-stranded DNA (ssDNA) translocase activities, as well as the ability to displace proteins from DNA.

First, it assists another protein, topoisomerase IIα (TOP2A), in untangling the DNA threads. Second, it works with a protein called BLM helicase to convert tangled threads into a simpler ...

First, it assists another protein, topoisomerase IIα (TOP2A), in untangling the DNA threads. Second, it works with a protein called BLM helicase to convert tangled threads into a simpler ...

Homologous recombination (HR) is important for DNA damage tolerance during replication. The yeast Shu complex, a conserved homologous recombination factor, prevents replication-associated mutagenesis.

Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then ...