How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

Pfizer Inc. today announced positive results from the Phase 3 TALAPRO-2 study of TALZENNA® (talazoparib), an oral poly ADP-ribose polymerase (PARP) inhibitor, in combination with XTANDI® (enzalutamide ...

DNA polymerases ... polymerase mutations or structural variations. Mutations or structural variation that have a strong affect on function of the canonical DNA polymerases (Fig. 1) would probably ...

Explore how psychosocial and physical stress affects cfDNA release in blood and saliva. Discover gender differences and ...

Destruction of islet cells with streptozotocin in mice induced hyperglycemia, intravascular oxidant production, DNA strand breakage ... in poly (ADP-ribose) polymerase-1 deficient mice.

Applied DNA Sciences, Inc. (NASDAQ:APDN) ("Applied DNA" or the "Company"), a leader in polymerase chain reaction ... and revenue surprises of 3.03% and 1.63%, respectively, for the quarter ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

While genetic testing rates for advanced ovarian cancer have increased, gaps in physician understanding and confidence in interpreting results may limit optimal biomarker-driven treatment and patient ...

Guardant Health is overcoming skepticism with new cancer tests. Learn why GH stock is a buy, with strong growth and a shift ...

The process of transcription elongation by RNA polymerase II (Pol II), in which Pol II travels along DNA and synthesizes RNA ... II stability via Cullin 3–ARMC5 recognition, Science Advances ...

Despite research showing the benefits of circulating tumor DNA as an indicator of disease remission in B-cell lymphoma, ...

Researchers determined the clinical classification of more than 90% of potential BRCA2 variants of uncertain significance in ...