DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

Understanding enhancer function is very important, since they contain the majority of genetic variants (‘mutations’) associated with common diseases, such as autoimmune, metabolic and neurological ...

The enhancers in this metaphor would be in charge of the amount of ingredients rather than their kind. Using sawdust instead of flour is an example of a genetic mutation, which is similar to ...

In a 2010 Nature paper, researchers in the lab of neurobiologist Michael Greenberg at Harvard Medical School reported that enhancers can produce RNA. Working with cultured mouse neurons, the ...

“We didn’t think it would work.” The results serve as an extreme example of what scientists are now recognizing as trends among enhancers—that activity can be conserved over long evolutionary ...

Experiments with shadow enhancers that influence the production of hair-like projections, which are called trichomes, on the bodies of fruit flies showed that, when the researchers deleted these ...

By poring over DNA sequences of zebrafish and human enhancers, the team noticed that only some of them were conserved, whereas others had largely non-conserved genetic code. Sequence-conserved ...

With single-base resolution data, we will be able to precisely identify changes at individual gene enhancers, providing a detailed molecular ... About duet evoC The combinatorial genetic and ...

New sequencing approach resolves the genetic complexity of a rare Mendelian conditionMENLO PARK, Calif., Jan. 29, 2025 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB), a leader in high-quality, long-read ...