Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ ... and structural modeling to show that the enzyme [MoCu]-CO dehydrogenase interacts with ...

A mechanism that could help scientists harness enzymes for use in drug discovery has been discovered in a research ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

Generations of students have been introduced to this subject with the first and second editions of Enzyme structure and mechanism by Alan Fersht. The detailed introductory descriptions of stopped ...

Instead of the enzyme mechanism described in biochemistry text-books, hen lysozyme hydrolysis was postulated to occur by a ring-opening mechanism based on substrate interactions defined by the active ...

Male ruffs have the ability to eliminate excess sex hormones from their bloodstream. We often associate high testosterone ...

Uncovering similar mechanisms in other organisms could inspire new strategies to target diseases linked to transcription-related genome instability. "We predict that other enzymes likely serve ...

The SCAN enzyme is at the heart of this discovery, as it uses a unique mechanism to attach NO to specific proteins, including those crucial for insulin signaling. The Role of SCAN and Nitric Oxide ...

(b. 1964) B.S., 1986, University of Massachusetts, Amherst; Ph.D., 1991, Brown University; National Institutes of Health Postdoctoral Fellow, 1991 – 1994 ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

Redox enzymes are proteins that catalyze oxidation-reduction reactions, which involve the transfer of electrons between ...