Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, ...

Pharmaceutical ads are difficult to avoid in American television programming and a growing number of them promote a class of ...

High resolution crystal structures of SF1 enzymes in complex with DNA and various nucleotide analogues have led to detailed proposals for ssDNA translocation through 'inch-worm' mechanisms that ...

Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery.

A new study has identified an enzyme that plays an important role in breaking down unneeded or damaged proteins in the heart – an important process for maintaining heart health.

Redox enzymes are proteins that catalyze oxidation-reduction reactions, which involve the transfer of electrons between molecules. Redox enzymes are ...

Rheumatoid arthritis (RA) is an autoimmune disorder affecting millions worldwide, causing chronic inflammation, debilitating ...