The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
EurekAlert!1d
Splicing twins: unravelling the secrets of the minor spliceosome complex
Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...
The spliceosome: An atomic-level look into how cells avoid errors when manufacturing mRNA
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
AZoLifeSciences on MSN6d
How Proteins Are Made: From DNA to Function
Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...
News Medical7d
Dysregulation of RNA-binding proteins in rheumatoid arthritis and osteoarthritis
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
Armed robbery in Revesby7d
RNA Binding Protein Role in Arthritis Unveiled via SC Transcriptomics
Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...
EurekAlert!8d
Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
GEN23d
First Synthetic Eukaryotic Genome Completed
This achievement represents the completion of the global Sc2.0 project to create the world’s first synthetic eukaryotic genome from Saccharomyces cerevisiae (baker’s yeast) and a new-to ...
GEN24d
Nipah Virus Polymerase Complex Structure Solved
Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex ... for both transcription and RNA replication and mutations that have ...
Nature4mon
The complex eukaryotic transcriptome: unexpected pervasive transcription and novel small RNAs
Indeed, eukaryotes show a remarkable ability to ... It allows the mapping of elongating RNA polymerase II 27. In this technique, cDNA probes are hybridized to DNA microarrays that carry ...
technologynetworks6mon
Prokaryotes vs Eukaryotes: What Are the Key Differences?
Every living organism falls into one of two groups: eukaryotes or prokaryotes, with cellular structure determining which group an organism belongs to. Prokaryotes are unicellular and lack a nucleus ...
Nature1y
The cap-to-tail guide to mRNA turnover
The biosynthesis of a translationally competent eukaryotic mRNA requires many events to be initiated by RNA polymerase II (Ref. 2). A 5′ 7-methylguanosine cap structure is incorporated co ...