The different positions and movements of the extracellular region appear to be an important way to activate the receptor. "This opens up new opportunities for drugging adhesion GPCRs, because now ...

Cysteinyl leukotrienes (CysLTs) are potent bronchoconstrictors, playing pivotal roles in inflammatory diseases. These lipid ...

For example, membrane receptors bind and respond to specific molecules outside the cell, such as hormones, neurotransmitters, the extracellular matrix, and attachment molecules on other cells.

Because membrane receptors interact with both extracellular signals and molecules within the cell, they permit signaling molecules to affect cell function without actually entering the cell.

ionophores, calcium chelators, as well as ligands for intracellular and extracellular receptors. "We had found a gene and the GPCR it encoded, ...

In a new study, researchers from Japan found that aromatic clusters on the extracellular receptor Siglec-14 found on macrophages recognized carbon nanotubes and then mediated an immune reaction to ...

More information: Yen‐Ting Lu et al, Small Extracellular Vesicles Engineered Using Click Chemistry to Express Chimeric ...

Other important cellular functions involving phospholipids are: extracellular receptor signaling, intracellular second messengers, ion exchange and cellular pressure regulation. There are several ...

Recently, it has become clear that glycosylation as well as other posttranslational events play a crucial role in the temporal and spatial regulation of signal transmission by altering extracellular ...