Intra-ImmuSG seeks to develop a safer and more effective cancer therapy via a combination of a targeted therapy and immunotherapy.

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Research reveals that δ-receptor agonists like KNT-127 alleviate IBS symptoms by modulating gut-brain interactions and ...

Initiation of Phase 1/2 combination trial with PYX-201, an extracellular ADC targeting Extradomain-B Fibronectin (EDB+FN) and Merck’s KEYTRUDA® ...

Hence, researchers often simulate the brain as a network of coupled neural masses, each described by a mean-field model. These models capture the essential features of neuronal populations while ...

Lung metastases are a devastating reality for over half of cancer patients whose tumors spread beyond their initial sites. These secondary lung tumors develop in part because of unique conditions ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

Small extracellular vesicles (sEVs ... cells to target death receptor 5 (DR5). Their experimental approach suppressed tumor growth and prolonged survival in models of melanoma, breast, and ...

This study sought to determine the potential of extracellular vesicle (EV) microRNAs (miRNAs) to serve as early diagnostic biomarkers for AMI. Peripheral blood samples were collected from three ...

The DR5 death receptor appears to have evolved ... Xu and his team used extracellular vesicles to target DR5 because these nano-sized capsules—about a million times smaller than a T cell ...