A collaborative team from the University of Macau and Nanjing University found, using clinical databases and samples, that the loss of a protein named MFG-E8 in nucleus pulposus (NP) tissue is a ...

As the world's population ages, intervertebral disk degeneration (IDD) has become a major medical issue, causing chronic ...

The Incucyte ® Live-Cell Analysis System is a fully automated platform for phase contrast and two-color fluorescence imaging, ...

EpiBiologics, a leader in tissue-selective extracellular protein degradation, today presented the first preclinical data on its EpiTAC bispecific antibody degrader of c-Met, a potential first-in-class ...

A recent study by researchers from Texas A&M University presented a new vaccine designed to target the ligand-binding domain of the serotonin 2A receptor (5-HT2AR), which resides in the second ...

Used for treatment of HER2-positive metastatic and early breast cancers ...

In regenerative science, B7-33's potential to influence fibroblast activity and collagen turnover suggests possible implications for tissue repair and wound healing. Given that fibrosis is often a ...

A new study shows that when energy is depleted—such as during a stroke—neurons begin releasing glutamate in abnormal, self-amplifying bursts that can damage nerve cells.

Our brain requires a constant supply of energy. A disrupted energy supply, as, for instance, caused by a stroke, can have ...

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...

Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

Unger was able to nip calcium transients in the bud by injecting a “puff” of sTREM2 into the mouse brain with a pipette; this temporarily silenced nearby neurons, and it did so in wild-type or TREM2 ...