Apoptosis is a highly regulated and critical homeostatic process in multicellular organisms. Aberrations in this form of programmed cell death have been implicated in several pathological conditions ...

Selective modulation of the apoptotic machinery has been the goal of oncology developers for more than two decades. The field continues to face special challenges. Many of the targets are ...

Altogether, these examples demonstrate how autophagy can prevent apoptosis and show the metabolic pathways through which cytoprotective autophagy can be stimulated. Autophagy-mediated cellular ...