Glucagon-Like Peptide-2 (GLP-2 ... chylomicrons—particles that transport fats in the bloodstream—through a signaling pathway involving neuronal nitric oxide synthase (nNOS)[2].

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

Studies by Jeffrey Klomp et al. 6 and Jennifer Klomp et al. 7 refine our understanding of the signaling effects of oncogenic KRAS. The studies suggest that mutant KRAS signals predominantly ...

This important study presents genome-wide high-resolution chromatin-based 3D genomic interaction maps for over 50 diverse human cell types and integrates these data with pediatric obesity GWAS. The ...

Background and aim: The importance of the hepatocyte ploidisation pattern to the control of cell proliferation and differentiation has been well established. However, there are no data that have ...

Furthermore, recent studies also have shown that TLR signaling can directly regulate the T cell activation, growth, differentiation, development, and function under diverse physiological conditions.

The effect of HGF/c-Met signaling on the promotion of CXCL16 production from ... Molecular cloning and expression of human hepatocyte growth factor. Nature. 1989 Nov 23;342(6248):440-3. [2]Hosonuma M, ...

Various cells in the liver, mainly hepatocytes, macrophages ... a Phosphodiesterase inhibitor, and TGF-β signaling inhibitors. FIGURE 3. Potential candidates for hepatic fibrosis and their mechanisms ...

Correspondence to Professor Bernd Schnabl, Department of Medicine, University of California, San Diego, CA 92093, USA; beschnabl{at}ucsd.edu The spectrum of non-alcoholic fatty liver disease (NAFLD) ...