In this review, we highlight the regulations and mechanisms of Hippo- YAP1/TAZ signaling in MASLD by focusing on metabolism, senescence, ferroptosis, inflammation, and fibrosis. Metabolic disorders ...

Metabolic requirements of dividing hepatocytes are prerequisite for liver regeneration after injury. In contrast to transcriptional dynamics during liver repair, its metabolic dependencies remain ...

Insulin lowers blood glucose by promoting its uptake into cells, while glucagon raises it by signaling the liver to release glucose from stored sources. Glucagon is secreted to the blood by alpha ...

Studies by Jeffrey Klomp et al. 6 and Jennifer Klomp et al. 7 refine our understanding of the signaling effects of oncogenic KRAS. The studies suggest that mutant KRAS signals predominantly ...