Glutamate excites neurons, creating the electrical activity essential for normal brain function. This excitatory transmission occurs through several specialized receptors, including NMDA ...

The study provides intriguing evidence linking autophagy to the removal of AMPA receptors from the cell membrane of LHb neurons. These receptors respond to the neurotransmitter molecule glutamate ...

NEW YORK CITY, NEW YORK / ACCESS Newswire / April 22, 2025 /Neurovation Labs, Inc., a precision neuroscience biotechnology ...

NEW YORK CITY, NEW YORK / ACCESS Newswire / April 22, 2025 / Neurovation Labs, Inc., a precision neuroscience biotechnology company targeting physiological biomarkers of Post-traumatic Stress Disorder ...

Illustration of an AMPA receptor and glutamate. Credit: Edward Twomey, Johns Hopkins Medicine Scientists used advanced cryo-EM imaging to reveal how glutamate activates brain receptors, paving the way ...

These drugs function by modulating ion channels, enhancing GABAergic inhibition, and blocking glutamate receptors. By stabilizing neuronal activity, AEDs reduce the occurrence of seizures and improve ...

The protein encoded by the GRIN2A gene is a member of the glutamate-gated ion channel family ... analysis demonstrated that deletion of activity-dependent synaptic AMPA receptors (AMPARs) had the ...

Our brain requires a constant supply of energy. A disrupted energy supply, as, for instance, caused by a stroke, can have ...

A new study shows that when energy is depleted—such as during a stroke—neurons begin releasing glutamate in abnormal, self-amplifying bursts that can damage nerve cells.