Researchers used advanced cryo-electron microscopy to capture atomic-level images of how glutamate, a key neurotransmitter, ...

Scientists used advanced cryo-EM imaging to reveal how glutamate activates brain receptors, paving the way for new ...

Discover how the brain's most abundant neurotransmitter, glutamate, is revolutionizing psychiatry and offering new hope for ...

Its landing place on neurons is a channel called an AMPA receptor, which interacts with glutamate, and then acts like a pore that takes in charged particles. The ebb and flow of charged particles ...

Glutamate receptors are required for the induction ... during LTP and LTD. The discovery of proteins that directly bind to AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid) receptor ...

So far, we have identified several novel features related to functions and regulation of AMPA and kainate-type glutamate receptors at the developing synapses. Our current research aims to understand ...

Sea's molecules act as selective dual AMPAR (AMPA receptor), KAINR (kainate receptor) antagonists (DAKAs). DAKAs dampen the activity of the excitatory neurotransmitter glutamate which plays an ...

Glutamate excites neurons, creating the electrical activity essential for normal brain function. This excitatory transmission occurs through several specialized receptors, including NMDA ...