the majority of which are ‘glutamatergic’. This means that the presynaptic neuron releases the neurotransmitter glutamate, which crosses the synaptic gap to bind to receptors — usually ...

Glutamatergic medications are a class of drugs that target the glutamate neurotransmitter system in the brain. These medications function by modulating glutamate neurotransmission and receptor ...

These receptors respond to various ligands ... D1R-IP3 signaling leads to adenosine release, which decreases glutamatergic transmission to NAc medium spiny neurons. Mice lacking functional ...

The group focuses on studying the mechanisms guiding activity-dependent development of glutamatergic circuitry in the limbic system and in particular, the roles of ionotropic glutamate receptors in ...

Although compounds with a combined cholinergic–glutamatergic action have been trialed, none has yet been successful in the later stages of development (Table 4). Consequently, combination ...