Early treatment with intravenous bisphosphonates at first radiographic evidence of bone lesions in patients with solid tumors or evidence of osteopenia in patients with multiple myeloma can ...

Ibandronate (as sodium) 3mg/3mL; soln for IV inj. Ibandronate inhibits osteoclast ... surgery). History of bisphosphonate exposure: evaluate for atypical fractures if thigh/groin pain develops ...

IV hydration is not typically necessary; however, patients should be encouraged to drink 2 glasses of water before bisphosphonate infusion. A physician should be consulted prior to administering ...